Erectile dysfunction drug helps men who have issues with ejaculation and orgasm
A new study suggests that the erectile dysfunction drug Cialis may also be beneficial in helping men who have problems with ejaculation and orgasm.
The study is the first to analyze the benefit of an agent like Cialis for issues of sexual dysfunction that extend beyond erectile dysfunction.
Approximately 70 per cent of men who used Cialis during sexual activity for 12 weeks were able to ejaculate most of the time and to reach orgasm, compared to 30 per cent in the placebo group.
Also, these benefits from the drug were seen despite the level of a man’s erectile dysfunction severity.
“There are many men who have, at most, very mild problems achieving an erection but who cannot easily ejaculate,” said study author Dr. Darius Paduch, a urologist and male sexual medicine specialist at NewYork-Presbyterian/Weill Cornell.
“Our study shows Cialis works very well for these men with problems ejaculating.”
Paduch said up to 18 per cent of men have a normal erection but don’t ejaculate, or take a long time to do so.
He added that while the issue may be more prevalent in the elderly, it affects men of all ages.
“Many of my patients are young men who want to have children and so they want to solve their issues with ejaculation,” Paduch said.
“Every internist faces this problem in his male patients and has no options to offer. Our study shows Cialis may help.”
Paduch and his colleagues have long researched issues of sexual dysfunction that extend beyond erectile dysfunction. “Erectile dysfunction isn’t the whole story, by any means,” he says.
A 2011 study led by Paduch helped clarify the issue.
The study followed nearly 12,130 men with mild to severe erectile dysfunction and found that 65 per cent of the participants were unable to have an orgasm and 58 percent had problems with ejaculation.
Even men with no or very minimal erectile dysfunction reported poor ejaculatory function (17 per cent) and poor ability to have an orgasm (22 per cent).
Paduch points out that approximately 30 million American men — half of all men aged 40 to 70 — have trouble achieving or sustaining an erection.
“Non-erectile sexual dysfunction is underreported and undertreated due to social stigma and, in particular, misunderstandings about the physiology of male sexual response and orgasmic dysfunction,” said Paduch.
“For decades it was believed that only women had problems with orgasm, but our research shows that orgasmic dysfunction could be as prevalent among men as it is among women.”
In the new study, Paduch and his colleagues examined data from 17 placebo-controlled 12-week trials of Cialis, given at different doses.
The studies included 3,581 participants with a mean age of 54.9, including 1,512 men with severe ejaculatory dysfunction and 1,812 with severe orgasmic dysfunction.
In some cases, patients with one or both of these conditions reported only mild or moderate erectile dysfunction.
The researchers examined the study participants’ responses on questionnaires about the effect Cialis had on erectile dysfunction, ejaculatory dysfunction, and orgasmic dysfunction, among other measures of sexual satisfaction.
The original questionnaire was primarily focused on the effects of Cialis on erectile dysfunction, but provided valuable additional information.
They found that treatment with Cialis (10 or 20 milligrams taken as needed) was associated with significant increase in ejaculatory and orgasmic function across all levels of severity of erectile dysfunction, ejaculatory dysfunction, and orgasmic dysfunction, compared to use of a placebo agent.
For example, 66 per cent of men with severe ejaculatory dysfunction and 66 percent with severe orgasmic dysfunction who used Cialis reported improved ejaculatory function, compared with 36 per cent and 35 per cent, respectively, in the placebo group.
Also, patients with moderate dysfunction also experienced significant improvements with Cialis.
“More study is needed, but we are hopeful our findings may lead to a treatment for many men who cannot now achieve sexual satisfaction,” says Paduch.
Other study co-authors include Alexander Bolyakov, a research associate in the Department of Urology at Weill Cornell, and Paula K. Polzer and Steven Watts, the study’s senior investigator, both of Lilly Research Laboratories of Eli Lilly. The study was published in the British Journal of Urology International.